What Is Hydroxyzine
Hydroxyzine is an antihistamine drug used to cure allergies. Histamine is released in the body during allergic disorders like common cold. This binds to the histamine receptor cells in our body. Histamine causes allergic reactions like sneezing, running nose and itching. Hydroxizine in its acive state is available as cetrizine. This drug causes sedation and has addictive tendencies. Hydroxyzine is more sedative than cetrizine. Because of sedation causing ability, this drug is used to as a sedative before applying surgical procedure.
This drug is available under brand names Atarax and Vistaril. Vistaril is pamoate salt formulation and atarax is hydrochloride as well as dihydrochloride salt formulation. Hydroxyzine hydrochloride is available in the form of tablets, syrups and injections. Vistaril is available as capsules.
Hydroxyzine is absorbed in gastro-intestinal tract and is metabolized by the liver. It starts acting within 15 to 30 minutes of intake and effect is sustained for 4 to 6 hrs. It helps in managing pruritus (itching) caused by allergy.
Hydroxyzine is not helpful to the patients who are sensitive to hyroxyzine or cetrizine. Also females in early pregnancy should avoid its use. Sedative tendencies of hydroxyzine make it helpful in curing anxiety disorders. These are also helpful in curing neurological disorders like psychoneurosis.
Hydroxyzine acts best when taken intramuscularly but it can taken orally also. Overdose may cause confusion and abnormality in behavior. This drug is lovable as it does not cause any dependence but its use is suggested to be avoided among elderly people.
Hydroxyzine is advisable to be taken during night because of sleep-inducing tendency. It is not at all advisable to drive after taking this medicine. People with medical history of breathing problems like asthma and other complications like glaucoma, heart problems, liver problems, seizures and enlarged prostrate should inform physician in advance before going for hydroxyzine treatment.
Drowsiness, blurred vision and headache are some of the side effects that may occur due to hydroxyzine intake. A serious allergic reaction is unlikely but doctor should be consulted immediately in case of itching, rashes, dizziness and difficulty in breathing.
Hydroxyzine hydrochloride is designated as C21H27ClN2O2.HCl chemically. Hydroxyzine hydrochloride occurs as white, odorless powder which is water soluble. This medicine is hypnotic and induces long sleep hours. This makes it suitable for curing anxiety disorders also.
Dosage of antihistamine is determined by various factors like age, weight and physical condition of the patient. It is an H1 receptor antagonist and was synthesized in 1950. Drugs related to this drug are buclizine, cyclizine and meclizine. These medicines are like clones of this drug and act very much similar to it. This drug is incompatible with aminophylline, benzylpenicillin salts, thiridazine, dimenhydrinate and some barbiturates. It can be taken with or without food.