What is Lipicon-S Tablets
Cardiovascular diseases are the major cause of deaths in adults in most developed and many developing ones and now the commonest cause of world wide.Dys lipidaemis are the major risk factor of atherosclerosis. It is commonly named coronary heart disease (CHD) and peripheral vascular disease. Elevated levels of low –density lipoprotein cholesterol (LDL-C) are associated with risk of CHD. The presence of other risk factors like age, smoking, family history, high blood pressure and diabetes influence the use of cholesterol-lowering drugs: diabetic from a particular at risk group fromCHD.
The goal of therapy in patients with dyslipidaemia to achieve lipid level to reduce the risk of development of CHD or to retard atherosclerosis in patient with CHD. Chloestyramine and Cholestipol have been shown to reduce risk of CHD but they are associated with many side effects. HMG COA reductase inhibitors are very effective for lowering LDL cholesterol level and have few short term side effects.
SIMVASTAIN has a long term efficacy and safely profile. It lowers the plasma level of LDL-C, total cholesterol (TC) and triglycerides (TG) and significantly increases plasma level of high-density lipoprotein cholesterol (HDL-C)
NICOTNIC ACID and nicotinamide together represent the essential vitamin niacian in the diet, of these two only nicotinic acid is active as a lipid-modifying drug.nicotinic acid is preferred in patients with triglycerides level exceeding 200mg/dl because bile acid sequestrants tend to raise triglycerides levels.Combination drug therapy has been shown to decrease cholesterol level in hyperlipidemic patients.
So, in order to lower the amounts of deaths, the best option is to use the combination of simvastatin and nicotinic acid which is found to be considerable in controlling the disorder. LIPICON-S TABLETS are found to possess both these salts and therefore are effective enough to reduce the risk of cardiovascular deaths. Each lipicon-stablet contains simvastatin (5mg) and nicotinic acid (125mg).