What Is Ossification

Similar to the bone tissue formation ossification is a process that leads to the generation of new bone and thus, the establishment of a variety of bone layers. There are generally two processes that are involved. The first and the foremost is the intramembranous ossification, which is the direct conversion of the bone to the connective tissue and the other is of the type commonly referred to as the endochondral ossificiation. The latter involves the conversion of bone to the primitive connective tissue and nevertheless, the involvement of cartilage as well. In severe bone fractures where they are treated by means of the plaster of Paris, stabilization of the bone is done by means of the metal plate and screws, which are later head by the process of intramembranous osteogenesis.

Another type of ossification called as the heterotopic ossification is one such process that results in the generation of bone tissue which is atypical at times and specifically at an extraskeletal location. Traumatic heterotopic ossification is just another means of ossification that mostly occurs when individuals face a complication or an injury and then the process of ossification sets in. Mostly, calcification is also confused with the term ossification although calcification has to do more with the accumulation and the deposition of calcium salts and crystals in the tissue. However, calcification usually occurs during the process of ossification and the reverse does not.

The mechanism of ossification and bone development is usually unclear and however involves various growth factors and cytokines. Evolution of the bone and the structure still remain a question of concern and debate when it comes to the point of this structural element which is an integral component of the vertebrates. There is a hypothesis that states that bone was actually developed from the type of tissues that were initially intended to store up minerals in the body. Ideally, these calcium based minerals were stored in the cartilage and the bone eventually developed from this cartilage to become the element that is specified. In specific terms, it can be said that the bone is an exaptation from this cartilage, which became calcified as a process of evolution.

Also, this bony structure during the process of evolution tended to be more protective and thus serve as a means of protection for the various tissue and the tissue elements. Also it served as a means of an osmotic barrier and a protective structure that tended to hold with itself the various elements of the human body. Ossification thus became a process that led to the development of new bony layers where the human structure and function took a rapid change and evolvement. It is through this process called ossification that has led to the development of strong structural layers of the vertebral kingdom. 

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