What is Sertraline

It was one of the most prescribed anti depressants in the US market during the year 2007 and replaced other types of anti depressants as well. The efficacy is similar to that of the older type of tricyclic antidepressants, but the effects are much reduced here. The differences between the newly developed antidepressants are that, they are more subtle in action and thus the side effects are less pronounced as well. There are also well defined evidences that sertraline works better in many instances than fluoxetine, when it comes to treating depression of certain types. Also, it is widely recommended in the treatment of panic disorder, but the combination of cognitive behavioral therapy along with sertraline is one better treatment for obsessive compulsive disorder.

There are other side effects to this drug as well. Some of the most common contraindications are high rates of nausea, diarrhea, insomnia, sexual disorders and effects of cognition and vigilance as well. There is also an effect on the dopaminergic neurotransmission that could be related to the cognitive behavior of an individual. Pregnant women, who consume Sertraline exhibit the presence of Sertraline in fetal blood and this is related to a wide range of birth defects in children. As with other antidepressants, there might be a tendency for suicidal behavior in those consuming this anti depressant molecule.

The treatment regimen for Sertraline varies depending on the disorder and for people with certain disorders such as the OCD, the dosage is definitely prone to vary. It is indeed true that cognitive behavioral therapy is more effective in adults and children, however, a combination with Sertraline yielded more powerful results. There is also a review that Sertraline is used in the treatment of OCD that is a cormorbid factor for Tourette syndrome, nevertheless, this may cause exacerbation of the tics in patients with Tourette syndrome. Sertraline besides OCD is also used in the treatment of social phobia and panic disorder. The response to this treatment was higher in patients at a later onset of the disease rather than the initial stages. Also, based on the different rating scales, the clinician rated scales were much higher than that of the anticipated group and thus, the greatest improvement in the quality of life was observed.

According to Pfizer, this Sertraline is contradindicated in patients with monoaminase oxidase inhibitors and thus cannot be taken along with disulfiram. This is especially true when the medicine is prescribed to the elderly as well as patients with an impairment of the liver. The reason is that Sertraline is released slowly from the blood and thus, the exposure of the medicine in the human body is actually three times more when compared to the normal dosage. Despite the various pros and cons of the molecule, Sertraline is one effective molecule that helps in treatment of various psychotic disorders.

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