What Is Suboxone

Suboxone is a prescription medicine used to reduce opioid dependence. This is commonly known to those people who are very familiar with opium plant. It is the trade name of Buprenorphine which is derived from thebaine. Thebaine is an alkaloid of the poppy plant. The botanical name of poppy plant is Papaver somniferum.

This is a rehabilitation drug used to treat victims of opioid addiction. Its opioid addiction treating abilities were recognized by FDA in 2006 and initially it was used as analgesic by Reckitt Benckiser in 1980s.

This is a Schedule III Drug under United Nations’ Convention of Psychotropic substances in USA. These are available as sublingual tablets in the strengths of 2mg and 8mg. Suboxone tablets are available in hexagonal shape, orange color and taste like lime. People do not like its taste and find it difficult to travel after taking it.

Suboxone medication has achieved an innovative form in the shape of films. These films are easy to be kept out of the reach of children and are very easy to carry. Even taste is a bit more acceptable. It is a narcotic treatment very effective in curing opioid dependence.

Suboxone is combination of buprenorphine hydrochloride and naloxone hydrochloride mixed in the ratio of 4:1. Suboxone tends to interact with Benzodiazepines and antiretrovirals. Efavirenz, nevirapine are few of the antiretrovirals which show in increase in opium levels in the body if these are taken with Suboxone concomitantly. In such cases, low intake of Suboxone should be advised immediately.

Butrenorphine which is the main component of Suboxone is liable to be abused like morphin or other opium products. Hence, proper license should be obtained by practitioners while using Suboxone for treating chronic pains. Suboxone was used as pain reliever because of its nerve relaxing property. Its usage needs to be carefully monitored to prevent development of any kind of addiction.

Side effects of this drug include constipation, diarrhea, chills and stomach ache. Sweating, vomiting and weakness may also result from the use of this drug. Severe mood changes, swelling in various parts of body, rashes, fainting, failing concentration and dizziness are few symptoms which should be immediately addressed and usage should be stopped or revised as per the doctor’s advice.

In the human brain, there are opioid receptors. The drugs that activate these opioid receptors are called Opioid Agonists. There are three types of Opioid Anagonists. Suboxone belongs to the third type of Opioid Agonists. This drug has some saturation point to absorption known as ceiling effect. After reaching the ceiling effect point, drug stops affecting anymore. This ceiling effect makes it a safer drug. But its ineffectiveness to combat pain after this point makes patients prone to heavier dose of other strong substitute which may have addictive property. Ceiling effect prevents Suboxone from being abused and misused.

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