What Is Thalassemia
Thalassemia is a well-known blood disease wherein body starts developing an irregular type of hemoglobin. If the hemoglobin molecule’s chain is defected, then a person can cause annihilation of red blood cells, which originates anemia. Alpha and Beta globin are two proteins responsible for creating Hemoglobin. The same way Thalassemia is also divided two parts such as Alpha Thalassemia and Beta Thalassemia.
Ample kinds of Thalassemia are available, and each kind has numerous diverse subtypes. Furthermore, alpha and beta both are divided in Thalassemia two modes: Major and Minor.
Major Alpha Thalassemia can be the reason of death of unborn baby, but born children with major Beta Thalassemia are normal at delivery. Such babies can develop serious anemia throughout first few years of life.
People having minor infection of alpha and beta Thalassemia will get tiny red blood cells without symptoms. Some more signs of Thalassemia are malformation of bone in the fatigue, yellow skin, face, growth failure and breathing problem.
Treatment of Thalassemia is possible with three normal medications: Iron Chelation therapy, Blood transfusions and Folic acid supplements. Blood transfusion is responsible to provide healthy red-blood cells with standard hemoglobin, though the cells can be alive to 120 days only. Patient getting transfusion treatment has to repeat the course after some period.
Procedure of blood transfusion treatment can be differing as it depends on age of a person. If the patient is higher in age, the blood transfusion period goes down. Kids with the age between 7 to 8 years have to follow the blood transfusion procedure monthly. After eight years of age the risk of life increase’s time by time and patient has to take transfusion according to requirement. In such case, patient might require the blood transfusion process twice or thrice in a month.
Following the blood transfusion treatment can cause lever and heart disease because it leads to increase the iron level in the blood. Preventing the body from other danger and disease Iron chelation therapy is used. This therapy is capable of remove surplus iron quantity from the body.
Both treatments are beneficial, but their conditions and risk factors are dissimilar. Folic acid is another useful treatment, which is capable of build strong vigorous red blood cells. Another process known as a stem-cell transplant is also useful, though it is difficult because here the patient has to search for the donor all time.
Lots of study and exploration are on for developing and testing the curing procedures for Thalassemia disease. Scientists are regularly doing tests and trying different methods to cure the problem in a correct manner. However, still Thalassemia is turned as the big challenge for the experts as they still didn’t get the permanent solution for this disease. The treatment of Thalassemia is become the big challenge for mankind.